Here's another reason why Middlesex by Jeffrey Eugenides is so good:

As little children Milton and Tessie had shared the same bedrom and bathtub, but that was long ago. Up until recently, Milton thought of Tessie as his prim cousin. Whenever one of his friends expressed interest in her, Milton told them to give up the idea. "That's honey from the icebox," he said, as Artie Shaw might have. "Cold sweets don't spread."

And then one day Milton came home with some new reeds from the music store. He hung his coat and hat on the pegs in the foyer, took out the reeds, and balled the paper bag up in his fist. Stepping into the living room, he took a set shot. The paper sailed across the room, hit the rim of the trashcan, and bounced out. At which point a vioce said, "You better stick to music."

Milton looked to see who it was. He saw who it was. But who it was was no longer who it had been.

Theodora was lying on the couch, reading. She had on a spring dress, a pattern of red flowers. Her feet were bare and that was when Milton saw them: the red toenails. Milton had never suspected that Theodora was the kind of girl who would paint her toenails. The red nails made her look womanly while the rest of her--the thin pale arems, the fragile neck--remained as girlish as always. "I'm watching the roast," she explained.

"Where's my mom?"

"She went out."

"She went out? She never goes out."

"She did today."

"Where's my sister?"

"4-H." Tessie looked at the black case he was holding. "That your clarinet?"

"Yeah."

"Play something for me."

Milton set his instrument case down on the sofa. As he opened it and took out his clarinet, he remained aware of the nakedness of Tessie's legs. He inserted the mouthpiece and limbered up his fingers, running them up and down the keys. And then, at the mercy of an overwhelming impulse, he bent forward, pressing the flaring end of the clarinet to Tessie's bare knee, and blew a long note.

She squealed, moving her knee away.

"That was a D flat," Milton said. "You want to hear a D sharp?"

Tessie still had her hand over her buzzing knee. The vibration of the clarinet had sent a shiver all the way up her thigh. She felt funny, as though she were about to laugh, but she didn't laugh. She was staring at her cousin, thinking, "Will you just look at him smiling away? Still got pimples but thinks he's the cat's meow. Where does he get it?"

"All right," she answered at last.

"Okay," said Milton. "D sharp. Here goes."

That first day it was Tessie's knees. The following Sunday, Milton came up from behind and played his clarinet against the back of Tessie's neck. The sound was muffled. Wisps of her hair flew up. Tessie screamed, but not long. "Yeah, dad," said Milton, standing behind her.

And so it began. He played "Begin the Beguine" against Tessie's collarbone. He played "Moonface" against her smooth cheeks. Pressing the clarinet right up against the red toenails that had so dazzled him, he played "It Goes to Your Feet." With a secrecy they didn't acknowledge, Milton and Tessie drifted off to quiet parts of the house, and there, lifting her skirt a little, or removing a sock, or once, when nobody was home, pulling up her blouse to expose her lower back, Tessie allowed Milton to press his clarinet to her skin and fill her body with music. At first it only tickled her. But after a while the notes spread deeper into her body. She felt the vibrations penetrate her muscles, pulsing in waves, until they rattled her bones and made her inner organs hum.

Milton played his instrument with the same fingers he used for the Boy Scout salute, but his thoughts were anything but wholesome. Breathing hard, bent over Tessie with trembling concentration, he moved the clarinet in circles, like a snake charmer. And Tessie was a cobra, mesmerized, tamed, ravished by the sound. Finally, one afternoon when they were all alone, Tessie, his proper cousin, lay down on her back. She crossed one arm over her face. "Where should I play?" whispered Milton, his mouth feeling too dry to play anything. Tessie undid a button on her blouse and in a strangled voice said, "My stomach."

"I don't know a song about a stomach," Milton ventured.

"My ribs, then."

"I don't know any songs about ribs."

"My sternum?"

"Nobody ever wrote a song about a sternum, Tess."

She undid more buttons, her eyes closed. And in barely a whisper: "How about this?"

"That one I know," said Milton.